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Oxic encephalopathy, also known as toxic-metabolic encephalopathy, is a degenerative neurologic disorder caused by exposure to toxic substances.[1] It can be an acute or chronic disorder. Exposure to toxic substances can lead to a variety of symptoms, characterized by an altered mental status.[2] Toxic encephalopathy can be caused by various chemicals, some of which are commonly used in everyday life.[3] Toxic encephalopathy can permanently damage the brain and currently, treatment is mainly just for the symptoms.[4] "Encephalopathy" is a general term describing brain malfunctions and "toxic" asserts that the malfunction is caused by toxins or chemicals.[5] The most prominent characteristic of toxic encephalopathy is an altered mental status. Toxic encephalopathy has a wide variety of symptoms,[6] which can include memory loss, small personality changes, lack of concentration, involuntary movements, nausea, fatigue, seizures, arm strength problems, and depression.
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